目前对社区获得性MRSA的最新定义

Proposed definitions of community-associated meticillin-resistant Staphylococcus aureus (CA-MRSA)


B.C. Millara, A. Loughreya, J.S. Elbornb, c and J.E. Moorea, ,  

aNorthern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Belfast, UK

bDepartment of Respiratory Medicine, Queen's University, Respiratory Medicine, Belfast City Hospital, Lisburn Road, Belfast, UK

cRegional Adult Cystic Fibrosis Unit, Belfast City Hospital, Belfast, UK


Available online 31 July 2007.




Summary

A new type of meticillin-resistant Staphylococcus aureus (MRSA) is emerging as a significant pathogen in otherwise healthy individuals in the community. This MRSA is distinct from healthcare-associated (HA)-MRSA, in terms of epidemiology, microbiology and clinical manifestations. A considerable number of reports are beginning to appear describing the organism and associated infections in the literature. However, within these reports, there is a lack of consensus as to the terminology used to describe community-associated (CA)-MRSA. This confusion is further compounded with the recent emergence of nosocomial transmission of CA-MRSA within hospitals. The aim of this article is to highlight the differences between HA-MRSA and CA-MRSA and to propose standard definitions of the various subgroups of CA-MRSA.


Keywords: Community-associated MRSA; Panton–Valentine leukocidin; PVL