加热冷却装置造成全球结核分枝杆菌的嵌合体暴发

Heater-Cooler Devices Blamed for Global Mycobacterium chimaera Outbreak资料来源SHEA网站：http://www.shea-online.org/journal-news/press-room/press-release-archives/497-heater-cooler-devices-blamed-for-global-mycobacterium-chimaera-outbreak                      加热冷却装置造成全球结核分枝杆菌的嵌合体暴发在不同的国家中，进行心脏手术的患者已经感染了结核分枝杆菌的嵌合体。 纽约（2016年11月14日）-     结核分枝杆菌的嵌合体全球暴发，这是一种具有侵袭性，生长缓慢的细菌，与用于心脏手术加热冷却装置（HCD）有关，根据今天出版的美国卫生保健流行病学学会的感染控制和医院流行病学杂志上发表的一项研究表明，这项研究对最近的现场报告的暴发增加了临时指导，给医院和医疗卫生系统提供预防性的建议来减少感染的风险。 Heater-Cooler Devices Blamed for Global Mycobacterium chimaeraOutbreakCardiac surgery patients in various countries have been infected by M. chimaeraNEW YORK (November 14, 2016) – A global outbreak of Mycobacterium chimaera, an invasive, slow-growing bacterium, is linked to heater-cooler devices (HCD) used in cardiac surgery, according to a study published today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America. This study adds interim guidance to recent field reports on the outbreak, providing precautionary recommendations to hospitals and health systems to reduce the risk of infections.“It is surprising that a global outbreak like this could go unnoticed for years. This dangerous infection has put many patients at risk all over the world,” said Rami Sommerstein, MD, of Inselspital, Bern University Hospital in Switzerland, the lead author of the study. “Now that we know HCDs are the source, individual action from the different players (healthcare institutions, manufacturers, etc.) is needed to contain the ongoing patient risk. The most important action a hospital can take is to remove contaminated HCDs from the operating room and other critical areas. That is the only way to ensure that patients are protected from this infection moving forward.”HCDs are stand-alone devices needed for heat exchange in heart-lung machines used in some 250,000 surgeries annually in the U.S., according to the Centers for Disease Control and Prevention. In response to an increasing number of infections, investigators looked into hospital water sources and found M. chimaera in HCD water circuits – specifically, in the LivaNova 3T HCD used in most hospitals around the world. They also found the bacteria in air samples during surgeries with LivaNova HCDs, suggesting transmission through air particles.To prevent future cases of invasive M. chimaera infections, the researchers made the following recommendations for hospitals and health systems, as well as public health authorities, based on their personal experience with the outbreak:

• Ensure strict separation of contaminated HCDs from air of critical medical areas
• Educate clinicians on the risks for and dangers associated with M. chimaera
• Screen patients who had open heart surgery, heart transplantation or those who were exposed to ventricular assist devices and demonstrate prolonged and unexplained fevers.